Wednesday, 3 September 2008
An Unusual Form Of Inheritance May Have A Role In The Rising Rate Of Diabetes
DNA is the primary mechanism of inheritance; kids get half their genes from mamma and half from pa. However, scientists are hardly starting to understand extra kinds of inheritance like metabolic computer programming, which occurs when an insult during a critical period of development, either in the womb or soon subsequently birth, triggers permanent changes in metabolism.
In this field of study, the researchers looked at the effects of a diet high in saturated fat on mice and their young. As expected, they establish that a high-fat diet induced type 2 diabetes in the adult mice and that this upshot was transposed by stopping the diet.
However, if female mice continued a high-fat diet during pregnancy and/or suckling, their offspring too had a greater oftenness of diabetes development, even though the offspring were given a moderate-fat diet. These mice were then mated with healthy mice, and the next genesis offspring (grandchildren of the original high-fat fed generation) could develop diabetes as well.
In effect, exposing a fetal computer mouse to senior high levels of saturated fats can cause it and its materialization to assume diabetes, even if the mouse goes off the high-fat diet and its young are never straightaway exposed.
The survey used mice so it's not time to warn women to eat differently during pregnancy and breastfeeding but in the beginning research has shown that this genial of inheritance is at work in humans. For example, there is an increased risk of high blood pressure and cardiovascular disease in children born of malnourished mothers.
From the article: "Effects of High Fat Diet Exposure During Fetal Life on Type 2 Diabetes Development in the Progeny" by Donatella Gniuli, Alessandra Calcagno, Maria Emiliana Caristo, Alessandra Mancuso, Veronica Macchi, Geltrude Mingrone, and Roberto Vettor.
Article data link: http://www.jlr.org/cgi/content/abstract/M800033-JLR200v1
Corresponding Author: Donatella Gniuli, Istituto di Medicina Interna, Universita' Cattolica del Sacro Cuore, Rome
Source: Nick Zagorski
American Society for Biochemistry and Molecular Biology
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Sunday, 24 August 2008
Download Maria McKee mp3
Artist: Maria McKee: mp3 download Genre(s): Folk: Folk-Rock Folk Rock Discography: Peddlin Dreams (Advance) Year: 2005 Tracks: 12 High Dive Year: 2003 Tracks: 14 Maria McKee Year: 1996 Tracks: 11 Life Is Sweet Year: 1996 Tracks: 12 You Gotta Sin To Get Saved Year: 1993 Tracks: 10 After making her appoint as the gritty, soulful pencil trail isaac Bashevis Singer of roots rockers Lone Justice, Maria McKee embarked on an often-rewarding solo vocation. A aboriginal of Los Angeles, McKee was born in 1964; her half brother was Bryan MacLean, the guitarist and former vocaliser of the groundbreaking ceremony psychedelic striation Love. After poring over musical theatre as a stripling, McKee started acting on the L.A. club prospect in a duet with MacLean and as well teamed up with local vapors isaac Bashevis Singer Top Jimmy (world Health Organization elysian the Van Halen vocal of the like ring). A roots-music scene sprang up in L.A. during the other '80s, and McKee -- a soundbox politic music fan -- met like-minded guitar thespian Ryan Hedgecock; the two co-founded Lone Justice in 1982, and with McKee often penning material, the mathematical group became a local favourite. They sign with Geffen on the recommendation of Linda Ronstadt, simply in malice of extremely positive media attention, their deuce albums -- 1985's Solitary Justice and 1986's Shelter -- failed to sell good, hampered by slick production and a good sense of not-quite-fulfilled dominance. McKee went solo later on the latter record and released her self-titled debut in 1989, with Mitchell Froom producing. McKee scored a critical find with her instant album, 1993's You Gotta Sin to Get Saved, which was helmed by Black Crowes/Jayhawks manufacturer George Drakoulias. Its rootsy, rustic rock and McKee's ever more powerful vocals lED many reviewers to call it her to the highest degree amply realized work to date. She went on to bestow the song "If Love Is a Red Dress (Hang Me in Rags)" to the hit soundtrack of Pulp magazine Fiction, and in 1996 she released a tierce solo album, the much artier Life Is Sweet, on which she played all the guitar parts. McKee afterwards took a suspension from recording, during which time she extricated herself from her trade with Geffen in lookup of greater creative control. She ultimately returned in 2003 with another ambitious criminal record, High Dive. In 2004, McKee issued Live in Hamburg, her first released concert picnic. It was followed by Peddlin' Dreams in 2005 and Live Acoustic Tour 2006. Late December appeared in 2007 from Cooking Vinyl Records. |
Thursday, 14 August 2008
Scarlett Johansson: 'I'm Too Young To Marry'
Although she is engaged, Scarlett Johansson feels she is too thomas Young to wed her fianc� Ryan Reynolds.
The Lost In Translation actress announced her engagement to Definitely Maybe star lowest May, just over a year subsequently they began dating.
Johansson says: "We're merely enjoying our time. We're just of late - identical recently - engaged. So, you know, we're just taking it easy. And no big plan yet.
"But it's a good time, and we're just... enjoying our time to be young and engaged. I mean, I'm 23. There's no rationality to rush into it. Everything feels very natural and relaxed."
Wednesday, 6 August 2008
Frown
Artist: Frown
Genre(s):
Metal
Discography:
Features And Causes Of The Frozen Origin
Year:
Tracks: 10
 
Friday, 27 June 2008
Cannes Film Festival - Movie Reviews Indiana Jones And The Crystal Skull
Film critics who held off their reviews of Indiana Jones and the Kingdom of the
Crystal Skull when it premiered at the Cannes Film Festival last weekend are
having a go at it today (Thursday), the official opening day of the movie. Manohla
Dargis in the New York Times gives it merely a so-so critique. "There's plenty
of frantic energy here, lots of noise and money too, but what's absent is any sense
of rediscovery, the kind that's necessary whenever a filmmaker dusts off an old formula
or a genre standard," she writes. But who needs that? Ty Burr seems to ask in the
Boston Globe. What audiences want, he remarks, is "engaged nostalgia, I think,
and on that level Crystal Skull delivers. This isn't a reinvention but a reunion,
of characters, creators, even techniques." Mick LaSalle in the San Francisco Chronicle
faults director Steven Spielberg for insisting on making the action nonstop,
resulting in what he calls "probably the worst of the Indiana Jones movies." Nevertheless,
he adds, that action "is more inventive, more lovingly detailed and a lot more pleasurable
than anything you could hope to see in [other] action movies." Stephen Hunter in
the Washington Post welcomes back "the hero." There's a pleasure, he writes,
in seeing the Indiana Jones character. He "hasn't a crystal jaw, much less a glass
one. Hit him, he gets up and hits you back. He always figures out a way to win. ...
It's romantic manliness at its purest, almost but not quite schmaltz, ideally calcula
ted to please true believers and ironic snorters at once."
22/05/2008
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Thursday, 19 June 2008
Archive
Artist: Archive
Genre(s):
Rock
Trip-Hop
Soundtrack
Discography:
Live at the Zenith
Year: 2007
Tracks: 11
Lights
Year: 2006
Tracks: 11
Michel Vaillant
Year: 2005
Tracks: 14
Noise
Year: 2004
Tracks: 12
Londinium
Year: 1997
Tracks: 13
The trip-hop project Archive was formed by Darius Keeler and Danny Griffiths, wHO earlier met in 1990. The geminate released a few singles on their own Swam judge, worked with Genaside II, and formed Archive in 1994. Signed to Island, Keeler and Griffiths released their debut, Londinium, in 1997. After splitting briefly, the two re-formed and released their second album, Take My Head, on Independiente in 1999.
Ondskapt
Thursday, 12 June 2008
Friday, 6 June 2008
Juno star drops out of Rami horror movie
The 'Juno' star had agreed to play the lead role in the film, however scheduling conflicts have now forced her to withdraw.
Shooting was due to get underway on March 17 in a bid to wrap before the possible Screen Actors Guild strike on June 30, but was then delayed.
However, the new date clashed with Page's forthcoming roles in psychological thriller 'Peacock' and Drew Barrymore's directorial debut 'Whip It!'
A statement from producers Ghost House Pictures and financier Mandate Pictures, read: "We were racing to start production so that we could accommodate Ellen's schedule.
"But like so many other productions trying to start before the potential SAG strike date, this one needed more time and we had to push back the start of production."
Thursday, 5 June 2008
Franz Ferdinand announce intimate UK tour
The band are set to hit the road this month, kicking off the jaunt at the York Fibbers on June 21 and ending it at the Leeds Faversham on June 29.
NME.COM previously announced that Franz Ferdinand will play an intimate London show at the Macbeth venue on Monday (June 9).
The band are set to complete recording of their third album imminently. Tickets for the newly-announced shows will be available from 9am (BST) tomorrow (June 6).
Franz Ferdinand will play.
York Fibbers (June 21)
Hull Adelphi (22)
Bristol Thekla (24)
Bath Moles (25)
Yeovil The Orange Box (26)
Cardiff The Point (28)
Leeds Faversham (29)
To check the availability of Franz Ferdinand tickets and get all the latest listings, go to NME.COM/GIGS now, or call 0871 230 1094.
Jul 18, 2008 at Latitude Festival, Southwold -
Aug 29, 2008 at Connect Festival, Inveraray, Greenock -
More Franz Ferdinand tickets
Tellus 2
Artist: Tellus 2
Genre(s):
Trance: Psychedelic
Discography:
Addiction
Year: 2003
Tracks: 10
 
Indiana Jones And The Golden Box Office
Tori Spelling says she's expecting a girl
Spelling, who already has a one-year-old son with McDermott, revealed the news to People magazine.
The 34-year-old actress said: "I've always wanted a little girl since I'm such a girly girl, and Dean always wanted a little girl as well."
Speaking about when she was told that she is having a girl, she said: "I immediately started crying. I couldn't believe it. I have my beautiful little boy and now I'll have my little girl. It's amazing."
Spelling also said: "I can't wait to be a great mom and friend to her. I'm a little nervous to have a girl."
"But mostly, I'm just excited for the same reasons - to prove to myself that I can be an amazing mom to a little girl."
Spears' behaviour sparks fresh concerns
According to People magazine, the singer was spotted arguing with her friend Sam Lutfi as they returned from a short drive around Beverly Hills.
The magazine reports that Spears looked "visibly distraught" as she jumped out of the car at her home.
She then reportedly wandered around with her dog London in her arms, before sitting on a pavement, while paparazzi were snapping photographs of her.
Onlookers said that she "looked completely lost" and had tears in her eyes.
But the singer later told the photographers: "I'm fine. I'm... having a nice time with my dog."
The report also claims that Spears' most recent boyfriend Adnan Ghalib was later refused entry to her house.
Fourth Bourne film still a possibility
Speaking to Empire magazine at the Empire Awards about the speculation regarding a fourth film, Damon said: "I think it's one of these stories that has a life of its own. Not that we're against it, we're all for doing a fourth movie but it means coming up with a good story. There are a lot of things that would have to happen before we would sign up for it."
Reacting to Damon's response, Greengrass said: "He says yes? It's news to me. I think the truth is that it's a very well loved franchise, but we're in the process of trying to work out what kind of film you could make."
He continued: "If there is one, what would it be? How it could go? Without any pressure; without any commitment to it, but everybody loved the franchise. We love it, but none of us would want to go again unless we're sure there's a worthwhile film and that could take some time. You don't want to do that when you feel like you've got to make it and none of us need to, so that's where we are".
Elvis Presley - Elvis Medicine Bottle And Eltons Toaster To Be Auctioned
An empty medicine bottle from ELVIS' Graceland home and a toaster belonging to SIR ELTON JOHN are among the bizarre celebrity artifacts up for auction to raise money for charity.
Items including a Christmas card from Sir Paul MCCartney to Adam Ant, a wooden spoon signed by late Beatle John Lennon and Yoko Ono in 1969, will go under the hammer in New York in aid of the Music Rising organisation.
The charity, which was co-founded up by U2 guitarist the Edge, aims to help musicians in New Orleans affected by 2005's Hurricane Katrina.
The auction takes place on 31 May (08).
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Happy Mondays - Bez Bankrupt Again
HAPPY MONDAYS dancer BEZ has been declared bankrupt for a second time in less than four years.
The English star, real name Mark Berry, was first declared bankrupt in August 2004, but won $100,000 (GBP50,000) after taking part in a British reality TV series. He vowed the money would go towards paying off his debts - but on 31 March (08), he was once again declared insolvent at London's High Court.
Berry found fame with the Happy Mondays in the 1990s, with whom his unique dancing style became legendary. The band released their last album Uncle Dysfunktional in August 2007.
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